As the second half of the NFL season kicks off, the race to the playoffs is in full swing. Four teams enter Week 10 riding winning streaks of at least five games: New Orleans (7), Houston (6), New England (6) and the Los Angeles Chargers (5).

Week 10 kicks off on Thursday Night Football with an interconference matchup between the Carolina Panthers and the Pittsburgh Steelers at Heinz Field.

The New England Patriots travel to Tennessee to take on the Titans on Sunday in what will be Tom Brady’s 300th career appearance (including the postseason). He joins Brett Favre as the only quarterbacks to play in 300 career games.

The Seattle Seahawks visit the Los Angeles Rams on Sunday afternoon. Los Angeles looks to bounce back after losing their first game of the season last week in New Orleans.

See the full Week 10 preview.